Here’s what your doctor may recommend for treating various underlying conditions: Medical Approachesĭepending on the cause, neuropathy may be relieved by medications, vitamin supplements, physical or occupational therapy, splinting, or surgery. Controlling a chronic condition may not eliminate your neuropathy, but it can play a key role in managing it. Neuropathy does not usually clear up unless the underlying problem is relieved or removed. Pain receptors in the skin can also become oversensitized, so that people may feel severe pain from stimuli that are normally painless (for example, some may experience pain from bed sheets draped lightly over the body). Others may not detect pains that warn of impending heart attack or other acute conditions. Damage to these fibers may cause people to become insensitive to injury from a cut or that a wound is becoming infected. People may feel as if they are wearing gloves and stockings even when they are not. Sensory nerve damage may result in a general sense of numbness, especially in the hands and feet. Motor nerve damage causes muscle weakness, and symptoms may include painful cramps and muscle twitching, muscle loss, bone degeneration, and changes in the skin, hair, and nails. Neuropathic pain is often worse at night, seriously disrupting sleep and adding to the emotional burden of sensory nerve damage. Neuropathic pain is difficult to control and can seriously affect emotional well-being and overall quality of life. Symptoms are related to the type of affected nerve and may be seen over a period of days, weeks, or years. Peripheral neuropathy produces symptoms such as weakness, muscle cramps, twitching, pain, numbness, burning, and tingling (often in the feet and hands). Occupational neuropathies: Industrial and athletic injuries to nerves such as the stinger in football result in arm weakness and tingling.Amyotrophic lateral sclerosis (ALS): Gehrig’s disease, a disorder of the motor nerves resulting in progressive weakness of the limbs, facial and respiratory muscles, is the most serious of the neuromuscular disorders.Ulnar neuropathies are also included as a type of mononeuropathy. Mononeuropathies: Isolated numbness of the hands brought on by excessive keyboard work may be identified as carpal tunnel syndrome, also a treatable problem.Early evaluation with laboratory studies may uncover potentially treatable disease such as diabetes and vitamin B12 deficiency. Diabetic neuropathies: Tingling in the feet may be caused by a peripheral neuropathy.Chronic inflammatory demyelinating polyneuropathy (CIPD).In the early 1900s, Guillain, Barre´, and Strohl first described the syndrome in 2 patients who spontaneously recovered from a progressive ascending motor weakness with areflexia, paresthesias, sensory loss, and an elevated level of cerebrospinal fluid (CSF) protein. An acute, ascending, and progressive neuropathy characterized by weakness, paresthesias, and hyporeflexia.
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